Clinical Trial Shows FirstLine Therapy More Effective than AHA
Dietary Plan
A recent issue of the peer-reviewed journal Nutrition (2006, Vol.
22(2), pp. 104-113) featured the results of a 12-week clinical study with
postmenopausal women at risk for CVD. This human trial demonstrated a
greater improvement in established cardiovascular health markers when
comparing the FLT program to a standard American Heart Association
Step 1 dietary plan (AHAD) and exercise (Table 1).

Making the Case for FirstLine Therapy
The purpose of FLT case studies is to show how this particular TLC
program may be clinically beneficial in patients with altered body
composition. Below are highlights from 2 case studies.
Case Study
Highlights
CASE #1071:
Subject
- A 33-year-old Caucasian female with altered body composition and
increased CVD risk secondary to elevated total cholesterol/HDL-C ratio
and hsCRP
Plan
- The patient was placed on the FLT program, along with medical
food and supplements
Results
- At 13 weeks, a 5.7% decrease (41.4% to 35.7%) in body fat and a 5.7%
increase (58.6% to 64.3%) in lean body mass were noted
- After 17 weeks, the patient lost a total of 19 lbs and her hsCRP
status reduced from 4.72 mg/dL to 0.997 mg/dL (79% decrease), and her
total cholesterol/HDL-C ratio showed a 12% decrease (4.26 to 3.77)
Summary
- The dramatically positive results of this case study suggest that the
FLT program—which incorporates healthy lifestyle changes such as a
specialized dietary program, regular exercise, and targeted nutritional
supplements—may improve body composition and decrease CVD risk in
patients with these health concerns
CASE #1072:
Subject
- A 48-year-old Caucasian female with altered body composition,
hypercholesterolemia, perimenopausal hot flushes, and metabolic syndrome
Plan
- The patient was placed on the FLT program, along with medical
food and supplements
Results
- In 17 weeks, a 54% decrease (102 µ IU/mL to 47.1 µ IU/mL) in
postprandial insulin and a 13% decrease (227 mg/dL to 198 mg/dL) in
total cholesterol were observed
- After 48 weeks, the patient lost a total of 49 lbs. and her BMI
decreased from 36.6 kg/m 2 to 28.5 kg/m 2 (22% reduction)
Summary
- This case study demonstrated a positive, long-term effect on a patient
with altered body composition, hypercholesterolemia, elevated
postprandial insulin, and bothersome perimenopausal hot flushes with the
application of the FLT therapeutic lifestyle changes program